Inhaled pulmonary vasodilators in refractory hypoxemia
نویسندگان
چکیده
منابع مشابه
Inhaled pulmonary vasodilators in refractory hypoxemia
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/). Patients on invasive mechanical ventilation with persistent hypoxemia despite supplemental oxygen (FiO2) usually have significant shunt physiology and/or low cardiac output. If faced with refractory hypoxemia or acute right vent...
متن کاملEffects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension.
Inhaled nitric oxide (NO) causes selective pulmonary vasodilation and improves gas exchange in acute lung failure. In experimental pulmonary hypertension, we compared the influence of the aerosolized vasodilatory prostaglandins (PG) PGI2 and PGE1 on vascular tone and gas exchange to that of infused prostanoids (PGI2, PGE1) and inhaled NO. An increase of pulmonary artery pressure (Ppa) from 8 to...
متن کاملInhaled epoprostenol vs inhaled nitric oxide for refractory hypoxemia in critically ill patients.
PURPOSE The purpose of this is to compare efficacy, safety, and cost outcomes in patients who have received either inhaled epoprostenol (iEPO) or inhaled nitric oxide (iNO) for hypoxic respiratory failure. MATERIALS AND METHODS This is a retrospective, single-center analysis of adult, mechanically ventilated patients receiving iNO or iEPO for improvement in oxygenation. RESULTS We evaluated...
متن کاملPulmonary vasodilators.
Pulmonary vasodilators are an important treatment for pulmonary arterial hypertension. They reduce pulmonary artery pressure; improve hemodynamic function; alter ventilation/perfusion matching in the lungs; and improve functional quality of life, exercise tolerance, and survival in patients with severe pulmonary arterial hypertension. This paper reviews the currently available pulmonary vasodil...
متن کاملParadoxical Hypoxemia with Simultaneous Use of Pulmonary Vasodilators in a Case of PPHN
Persistent pulmonary hypertension of the newborn (PPHN) is characterized by the persistence of high pulmonary vascular resistance (PVR) of fetal life, after birth. Inhaled nitric oxide (iNO) has been the mainstay of PPHN treatment. Intravenous (IV) sildenafil and inhaled epoprostenol are newer agents, which are currently not FDA approved. We describe the first reported case of PPHN in which the...
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ژورنال
عنوان ژورنال: Clinical and Experimental Emergency Medicine
سال: 2015
ISSN: 2383-4625
DOI: 10.15441/ceem.15.078